Protein consists of a precise sequence of amino acids and fold into a specific three-dimensional shape or conformation. They have precisely engineered moving parts, and their mechanical actions are closely related to chemical events, which are the basis of dynamic processes in living cells. The interaction between protein and other molecules is the frontier and hotspot of life science research in the 21st century. Research has shown that a protein's ability to bind and interact with other molecules enables it to act as a catalyst, signal receptor, switch, motor or tiny pump. Various important physiological processes in cells, such as gene replication, transcription, translation, cell cycle regulation, signal transduction, immune regulation, cell differentiation and death, etc., are all accomplished through proteins and their interactions with other molecules. In view of the important functions of proteins, proteins have been intensively studied and widely used. Recombinant protein production is one of the most powerful technologies used in life sciences, enabling efficient expression of specific protein DNA in a variety of expression systems (such as bacteria, yeast, insect cells, and mammalian cells), which also makes proteins play an indispensable role in the fields of academia, medicine, and biotechnology.
Profacgen's broad service portfolio is designed to provide versatile and reliable platforms for protein production and research. Most CROs lack a global perspective and comprehensive technical platforms, so it is difficult to ensure the output of high-quality data and even lead to project failure. With years of experience in providing contract research services, Profacgen has experience in virtually all aspects of protein design, production, analysis, and application. Over the past 10 years, we have assisted thousands of researchers around the world to successfully complete their projects, including providing high-quality solutions to extremely challenging projects.
Our protein research services include but are not limited to:
Customized protein production platform, from proof-of-concept studies to pilot manufacturing to large-scale production. In addition to protein production, we also offer protein labeling, protein mutagenesis, glycoengineering, cell line development, and process and production development, among others.
A broad range of analytical reagents and services ensures comprehensive assessment of protein purity, identity, structural properties, conformational integrity and function. Our services include complement assays, interaction analysis of proteins and other molecules, biomarker development, and enzyme activity assays.
Bioinformatics Platform Introduction
Our bioinformatics platform has become a scientific infrastructure involving state-of-the-art computing facilities, providing powerful support for academic and industrial researchers to explore, understand and analyze complex biological data.
The Profacgen protein chemistry department has established the PROTAC platform, established the compound library of highly affinity small molecules and small molecule fragments of popular targeted proteins, which can be used for efficient ligand and targeting protein design, greatly accelerating the drug development process.
Profacgen laboratories are dedicated to offer comprehensive one-stop services for pre-clinical drug development, including pharmacology/toxicity studies as well as chemistry, manufacturing and controls (CMC) services worldwide, which aim to evaluate and improve the efficacy and safety of new drug candidates.
Experiment Consulting and Design Service
Profacgen designs feasible experimental plans for customers according to their experimental purposes, combining molecular biology, cell biology, omics, and current research hotspots.
Profacgen has accumulated lots of experience in protein production and analysis. Our professional technical team can provide customers with high-quality protein products and many related featured services. Our competitive prices and extensive expertise have earned us the trust of our collaborators. Contact us to find out how Profacgen could be of assistance.
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