Protein Co-expression
Multi-protein complexes play indispensable roles in a wide range of cellular processes, such as transcription, translation, RNA splicing, signaling cascades, protein trafficking, trafficking, and degradation. With the deepening of research, people are aware that the function of a protein is not only affected by its own physical and chemical properties, but also depends on its interactions with its partners, and the characteristics of them. At present, a lot of research is focused on the structure and function of multi-protein complexes, which have shown great potential in the biotechnology industry, metabolic engineering and even biopharmaceutical therapy. Reconstitution of multi-proteins by protein co-expression has become a recognized and powerful strategy, providing researchers worldwide with a fast and efficient method to generate complexes in soluble forms and to study protein-protein interaction networks.
Our Services
Co-expression of multi-proteins/complexes in E. coli is a useful alternative to complicated and expensive expression systems such as baculovirus or mammalian cell culture. Profacgen offers many expression strategies including co-expression from one vector, co-expression from different vectors, and a combination of both methods.
According to the characteristics of BEVS, Profacgen provides customers with single polycistronic baculovirus (co-expression), multiple monocistronic baculoviruses (co-infection), and a combination of the two.
Profacgen offers various strategies for the production of recombinant protein complexes in mammalian cells (HEK293, CHO) such as transient co-transfection, viral infection and stable integration of expression constructs into the host genome.
Why choose Profacgen:
- Customize the experimental program according to different needs
- Powerful and well-established expression platforms
- High quality, efficient and cost-effective
- One-stop service
Profacgen has accumulated lots of experience in protein co-expression. Our professional technical team can provide customers with high-quality protein co-expression services and assist in protein co-expression network analysis and interaction studies. Our competitive prices and extensive expertise have earned us the trust of our collaborators. Contact us to find out how Profacgen could be of assistance.