PROTAC in Vitro Evaluation

In 2001, PROTAC was first proposed as a chemical biological method and a new treatment method. After 20 years of development, PROTAC technology has been mature. PROTAC can not only effectively inhibit the target protein, but also be quickly degraded and cleared. One of the most noteworthy points is that only the amount of catalyzed drugs can degrade the intracellular target protein, so it has high safety, drug resistance and broad application prospects. Despite the apparent effectiveness of PROTACs, there are still a number of deficiencies that need to be addressed: for example, the ability of PROTAC to degrade POI cannot be evaluated in large quantities and quickly, membrane permeability is poor, and optimization needs to be analyzed.

Profacgen is a leading life science research and development company, professional for biopharmaceutical clients and partners from target identification to drug development of integrated drug development services, we provide professional PROTAC in vitro assessment services, provide sensitive compounds high-throughput screening test method, analysis and compare the effect of candidate compounds from every level and performance, fully support target design, optimization and transformation, efforts to solve the low PROTAC flux in drug development, compound complex mechanism and so on.

Profacgen provides the following services for you:

The service flow provided by Profacgen is as follows:

Profacgen has an experienced team that provides a variety of PROTAC services. Please contact us for specific project implementation content and time. If you want to know more service information, please feel free to contact us, Profacgen will be your trusted partner.