A New Optimized High Internal Phase Emulsions (HIPEs)

Most trans fats in processed foods come from partially hydrogenated oils (PHOs). Numerous studies have found that excessive intake of trans fats can have adverse effects on human health. A feasible and effective alternative to PHOs is constructing Pickering high internal phase emulsions (HIPEs). HIPEs offers a possible way to convert liquid oils into solid fats without trans or saturated fatty acids. In recent years, protein-based particle-stabilized Pickering high internal phase emulsions have gained extensive attention due to their high stability and applications in the food, cosmetic, and pharmaceutical industries.

Traditional high internal phase emulsions (HIPEs) are mainly stabilized by low-molecular-weight surfactants and biopolymers, which can adsorb on the surface of oil droplets and prevent the flocculation and binding of oil droplets. However, high internal phase emulsions are stabilized mainly by inorganic or synthetic organic particles, such as silica and magnetic nanoparticles, which present potential toxicity risks and environmental drawbacks. To address the pitfalls of potential toxicity, researchers investigated the use of renewable and biocompatible granules as stabilizers for HIPE, including starch granules, cellulose granules, and more. However, natural compounds suffer from solubility problems that limit their performance. Therefore, it becomes essential to explore the optimization of HIPE.

Recently, researchers have developed an optimized HIPE; this optimized HIPE is achieved by adding natural polysaccharides. The synthesis method is straightforward and does not require special equipment, and does not require the use of any surfactants, colloidal particles, monomers, or synthetic polymers. It can be obtained by simple centrifugation and sonication. This natural polysaccharide enhances the stability of HIPE and does not have any potential toxicity risk. This natural HIPE material exhibits unique advantages in controlling morphology, rheology, and processability and shows great potential in drug delivery.

The Advantages of this platform include:

• Natural material with no potential toxicity risk
• The controllable shape of the material
• Simple synthesis method, no need for complex instruments, and equipment

Potential Applications

• New materials for drug delivery
• Optimization of high internal phase emulsions
• A new method of nutrient transport

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Reference

1. Aldemir Dikici, Betül & Claeyssens, Frederik. (2020). Basic Principles of Emulsion Templating and Its Use as an Emerging Manufacturing Method of Tissue Engineering Scaffolds. Frontiers in Bioengineering and Biotechnology. 8. 10.3389/fbioe.2020.00875.