Recombinant Mouse Serpini1 Protein(Fc tag) (MH0256SL)

Recombinant Mouse Serpini1 Protein (O35684) (Met 1-Glu 215) with the Fc region of human IgG1 at the N-terminus was expressed in HEK293.

Datasheet

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PRODUCT INFORMATION

Cat.No.

MH0256SL

Synonyms

SERPINI1; neuroserpin; serpin I1; PI12; PI-12; Spi17

Accession

Serpini1

Predicted N Terminal

Glu

Form

Lyophilized from sterile PBS, pH 7.4, 5 % trehalose and 5 % mannitol.

Bio-activity

Measured by its ability to bind mouse AGER-His in functional ELISA.

Molecular Mass

Recombinant Mouse HMGB1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 475 amino acids and has a calculated molecular mass of 53.3 kDa. The apparent molecular mass of the monomer is approximately 57 kDa in SDS-PAGE under reducing conditions.

Endotoxin

< 1.0 EU per 1 microgram of protein (determined by LAL method).

Purity

> 85 % by SDS-PAGE.

Storage

In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). Avoid repeated freeze/thaw cycles.

Reconstitution

Reconstitute in sterile distilled water to a concentration of 0.1-1.0 mg/mL.

Warning

For research use only!

Background

Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.

Tag

Species

Mouse

Source

HEK293

BACKGROUND

Background