Recombinant Mouse Cd226 Protein(Fc-His tag) (MH0237CL)

Recombinant Mouse Cd226 Protein (Q8K4F0) (Met 1-Pro 254) with polyhistidine-tagged Fc region of human IgG1 at the C-terminus was expressed in HEK293.

Datasheet

Size	Price	Qty
50ug	$429.00

Order Online Bulk Inquiry

PRODUCT INFORMATION

Cat.No.

MH0237CL

Synonyms

CD226; CD226 antigen; Pta1; DNAM1; DNAM-1; TLiSA1

Accession

Cd226

Predicted N Terminal

Glu 19

Form

Lyophilized from sterile PBS, pH 7.4, 5 % trehalose and 5 % mannitol.

Bio-activity

Measured by its ability to bind recombinant mouse CD155/PVR. Immobilized recombinant mouse CD155/PVR at 1 μg/ml (100 μl/well) can bind recombinant mouse CD226/DNAM-1 with a linear range of 0.78-100 ng/ml.

Molecular Mass

Recombinant Mouse DNAM1/Fc is a disulfide-linked homodimer. The reduced monomer consists of 484 amino acids and has a predicted molecular mass of 55 kDa. As a result of glycosylation, rm DNAM1/Fc monomer migRates with an apparent molecular mass of 70-80 kDa in SDS-PAGE under reducing conditions.

Endotoxin

< 1.0 EU per 1 microgram of protein (determined by LAL method).

Purity

> 97 % by SDS-PAGE.

Storage

In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). Avoid repeated freeze/thaw cycles.

Reconstitution

Reconstitute in sterile distilled water to a concentration of 0.1-1.0 mg/mL.

Warning

For research use only!

Background

Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding.

Tag

Fc-His

Species

Mouse

Source

HEK293

BACKGROUND

Background