Recombinant Human SPAM1 Protein (HC0068SL)

Cat.No.

HC0068SL

Synonyms

SPAM1; HYAL5; PH 20; SPAG15; hyal-PH20; HYA1; PH20; HYAL1; HYAL3; PH-20;

Accession

SPAM1

Form

Normally 20-50mM NaAC-HAC and 100-150 mM NaCl are added, pH 5.0-6.0.

Molecular Mass

Recombinant Human SPAM1 Protein has a molecular mass of approximately 59-63 kDa.

Endotoxin

< 0.1 EU per 1 microgram of protein (determined by LAL method).

Purity

> 95 % by SDS-PAGE.

Storage

In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). Avoid repeated freeze/thaw cycles.

Warning

For research use only!

Background

Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.

Species

Human

Source

CHO

Background

Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.