Recombinant Human NPR1 Protein(Fc tag) (HH0081NL)

Recombinant Human NPR1 Protein (O14786) (Met 1-Lys 644) with the Fc region of human IgG1 at the C-terminus was expressed in HEK293.

Datasheet

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PRODUCT INFORMATION

Cat.No.

HH0081NL

Synonyms

NPR1; ANPa; GUCY2A; GC-A; ANP-A; NPR-A; ANPR-A; NPRA; ANPRA; GUC2A;

Accession

NPR1

Predicted N Terminal

Phe 22

Form

Lyophilized from sterile PBS, pH 7.4, 5 % trehalose and 5 % mannitol.

Bio-activity

Measured by its ability to bind with recombinant human VEGF165 in a functional ELISA.

Molecular Mass

Recombinant Human NRP1/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 861 amino acids and has a calculated molecular mass of 96.5 kDa. As a result of glycosylation, rh NRP1/Fc monomer migRates as an approximately 120-125 kDa protein in SDS-PAGE under reducing conditions.

Endotoxin

< 1.0 EU per 1 microgram of protein (determined by LAL method).

Purity

> 85 % by SDS-PAGE.

Storage

In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). Avoid repeated freeze/thaw cycles.

Reconstitution

Reconstitute in sterile distilled water to a concentration of 0.1-1.0 mg/mL.

Warning

For research use only!

Background

Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Can induce angiogenesis (PubMed:23469107).

Tag

Species

Human

Source

HEK293

BACKGROUND

Background