Recombinant Human IL2RB Protein(Fc tag) (HH0138IL)

Recombinant Human IL2RB Protein (P14784) (Met 1-Asp 239) with the C-terminal Fc region of human IgG1 was expressed in HEK293.

Datasheet

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PRODUCT INFORMATION

Cat.No.

HH0138IL

Synonyms

IL2RB; CD122; p75; IL-2RB; IL15RB; P70-75;

Accession

IL2RB

Predicted N Terminal

Ala 27

Form

Lyophilized from sterile PBS, pH 7.4, 5 % trehalose and 5 % mannitol.

Bio-activity

Measured by its ability to bind biotinylated recombinant rat IL2 in a functional ELISA. Using the Octet RED System, the affinity constant (Kd) of Human IL2RB-Fc bound to Human IL2 was 0.8nM.

Molecular Mass

Recombinant Human IL2 Rβ/Fc is a disulfide-linked homodimeric protein geneRated after removal of the signal peptide. The reduced monomer consists of 451 amino acids and has a predicted molecular mass of 51.6 kDa. As a result of glycosylation, the apparent molecular mass of rh IL2RB/Fc monomer is approximately 60-65 kDa in SDS-PAGE under reducing conditions.

Endotoxin

< 1.0 EU per 1 microgram of protein (determined by LAL method).

Purity

> 90 % by SDS-PAGE.

Storage

In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). Avoid repeated freeze/thaw cycles.

Reconstitution

Reconstitute in sterile distilled water to a concentration of 0.1-1.0 mg/mL.

Warning

For research use only!

Background

Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

Tag

Species

Human

Source

HEK293

BACKGROUND

Background

Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.