Recombinant Human ERBB2 Protein(His tag) (HH0078EL)

Recombinant Human ERBB2 Protein (P04626) (Met 1-Thr 652) with the polyhistidine tag at the C-terminus was expressed in HEK293.

Datasheet

Size	Price	Qty
50ug	$429.00

Order Online Bulk Inquiry

PRODUCT INFORMATION

Cat.No.

HH0078EL

Synonyms

ERBB2; CD340; HER 2; HER2; NEU; NGL; TKR1; HER-2; MLN 19; HER-2/neu;

Accession

ERBB2

Predicted N Terminal

Thr 23

Form

Lyophilized from sterile PBS, pH 7.4, 5 % trehalose and 5 % mannitol.

Bio-activity

Measured by its binding ability in a functional ELISA. Immobilized human Erbb2 at 2.5 μg/ml (100 μl/well) can bind Herceptin with a linear ranger of 1.28-32 ng/ml.

Molecular Mass

Recombinant Human ErbB2 comprises 641 amino acids and has a calculated molecular mass of 71 kDa. As a result of glycosylation, rh ErbB2 migRates as an approximately 100-110 kDa protein in SDS-PAGE under reducing conditions.

Endotoxin

< 1.0 EU per 1 microgram of protein (determined by LAL method).

Purity

> 90 % by SDS-PAGE.

Storage

In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). Avoid repeated freeze/thaw cycles.

Reconstitution

Reconstitute in sterile distilled water to a concentration of 0.1-1.0 mg/mL.

Warning

For research use only!

Background

Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages (By similarity).

Tag

His

Species

Human

Source

HEK293

BACKGROUND

Background