Molecular Mass
RecombinantHuman CD147/Fc chimera protein consists of 422 amino acids and has a calculated molecular mass of 46.8 kDa. As a result of glycosylation, Recombinant protein migRates as an approximately 58-65 kDa band in SDS-PAGE under reducing conditions.
Background
May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.