Lyophilized from sterile PBS, pH 7.4, 5 % trehalose and 5 % mannitol.
Bio-activity
Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 10-40 ng/mL in the presence of 10 ng/mL recombinant Activin A.
Molecular Mass
Recombinant Human ACVR2A/Fc chimera is a disulfide-linked homodimer protein geneRated after removal of the signal peptide. The monomer comprises 352 amino acids and predicts a molecular mass of 40.0 kDa. As a result of glycosylation, the monomer migRates as an approximately 60-65 kDa protein in SDS-PAGE under reducing conditions.
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method).
Purity
> 97 % by SDS-PAGE.
Storage
In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). Avoid repeated freeze/thaw cycles.
Reconstitution
Reconstitute in sterile distilled water to a concentration of 0.1-1.0 mg/mL.
Warning
For research use only!
Background
May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.
Tag
Fc
Species
Human
Source
HEK293
BACKGROUND
Background
May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.
Online Inquiry
Fill out this form and one of our experts will respond to you within one business day.