Recombinant Human ITGB2 Protein (His tag) (HI0044IS)
Recombinant Human ITGB2 Protein (NP_000202.2) (23-700aa) with C-terminus His tag was expressed in Insect cells.
| Size | Price | Qty |
|---|---|---|
| 50ug | $660.00 |
PRODUCT INFORMATION
Cat.No.
HI0044IS
Synonyms
ITGB2; MFI7; LFA 1; MAC 1; CD18; MF17; MFI7; LCAMB
Accession
Form
Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass
75.9kDa (686aa)
70-100kDa (SDS-PAGE under reducing conditions)
70-100kDa (SDS-PAGE under reducing conditions)
AA Sequence
QECTKFKVSS CRECIESGPG CTWCQKLNFT GPGDPDSIRC DTRPQLLMRG CAADDIMDPT SLAETQEDHN GGQKQLSPQK VTLYLRPGQAAAFNVTFRRA KGYPIDLYYL MDLSYSMLDD LRNVKKLGGD LLRALNEITE SGRIGFGSFV DKTVLPFVNT HPDKLRNPCP NKEKECQPPFAFRHVLKLTN NSNQFQTEVG KQLISGNLDA PEGGLDAMMQ VAACPEEIGW RNVTRLLVFA TDDGFHFAGD GKLGAILTPN DGRCHLEDNLYKRSNEFDYP SVGQLAHKLA ENNIQPIFAV TSRMVKTYEK LTEIIPKSAV GELSEDSSNV VQLIKNAYNK LSSRVFLDHN ALPDTLKVTY
DSFCSNGVTH RNQPRGDCDG VQINVPITFQ VKVTATECIQ EQSFVIRALG FTDIVTVQVL PQCECRCRDQ SRDRSLCHGK GFLECGICRCDTGYIGKNCE CQTQGRSSQE LEGSCRKDNN SIICSGLGDC VCGQCLCHTS DVPGKLIYGQ YCECDTINCE RYNGQVCGGP GRGLCFCGKCRCHPGFEGSA CQCERTTEGC LNPRRVECSG RGRCRCNVCE CHSGYQLPLC QECPGCPSPC GKYISCAECL KFEKGPFGKN CSAACPGLQLSNNPVKGRTC KERDSEGCWV AYTLEQQDGM DRYLIYVDES RECVAGPNLE HHHHHH
DSFCSNGVTH RNQPRGDCDG VQINVPITFQ VKVTATECIQ EQSFVIRALG FTDIVTVQVL PQCECRCRDQ SRDRSLCHGK GFLECGICRCDTGYIGKNCE CQTQGRSSQE LEGSCRKDNN SIICSGLGDC VCGQCLCHTS DVPGKLIYGQ YCECDTINCE RYNGQVCGGP GRGLCFCGKCRCHPGFEGSA CQCERTTEGC LNPRRVECSG RGRCRCNVCE CHSGYQLPLC QECPGCPSPC GKYISCAECL KFEKGPFGKN CSAACPGLQLSNNPVKGRTC KERDSEGCWV AYTLEQQDGM DRYLIYVDES RECVAGPNLE HHHHHH
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity
> 85% by SDS - PAGE
Storage
Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles.
Concentration
0.25mg/ml (determined by Absorbance at 280nm)
Warning
For research use only!
Background
This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.
References
Law SK., et al. (1987) EMBO J. 6:915-919.
Xu J., et al. (2008) Nat Immunol. 9:880-886.
Xu J., et al. (2008) Nat Immunol. 9:880-886.
Tag
His tag
Species
Human
Source
Insect cells
BACKGROUND
Background
This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.
References
Law SK., et al. (1987) EMBO J. 6:915-919.
Xu J., et al. (2008) Nat Immunol. 9:880-886.
Xu J., et al. (2008) Nat Immunol. 9:880-886.
