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Recombinant Human CD70 Protein (hIgG-His tag) (HI0029CS)

Recombinant Human CD70 Protein (NP_001243) (39-193aa) with C-terminus His tag was expressed in Insect cells.

Size Price Qty
50ug $660.00
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PRODUCT INFORMATION

Cat.No.
HI0029CS
Synonyms
CD70; CD70 molecule; CD70 antigen; CD27L; CD27-L; CD27LG; TNFSF7
Accession
Form
Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass
18.2kDa (164aa)
AA Sequence
ADPQRFAQAQ QQLPLESLGW DVAELQLNHT GPQQDPRLYW QGGPALGRSF LHGPELDKGQ LRIHRDGIYM VHIQVTLAIC SSTTASRHHP TTLAVGICSP ASRSISLLRL SFHQGCTIAS QRLTPLARGD TLCTNLTGTL LPSRNTDETF FGVQWVRPHH HHHH
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity
> 90% by SDS - PAGE
Storage
Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles.
Concentration
0.25mg/ml (determined by Absorbance at 280nm)
Warning
For research use only!
Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
References
Welten SP., et al. (2013) J. Virol. 87:6851-6865.
Polak ME., et al. (2012) J. Invest. Dermatol. 132:1636-1644.
Tag
His tag
Species
Human
Source
Insect cells

BACKGROUND

Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
References
Welten SP., et al. (2013) J. Virol. 87:6851-6865.
Polak ME., et al. (2012) J. Invest. Dermatol. 132:1636-1644.
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