Lyophilized from sterile 50 mM tris, 100 mM glycine, pH7.5, 10% Trehalose.
Molecular Mass
Recombinant Human TIGIT Protein is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 39.7 kDa. The reducing protein migrates as 40-55 kDa in SDS-PAGE due to glycosylation.
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method).
Purity
> 92 % by SDS-PAGE.
Storage
In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). Avoid repeated freeze/thaw cycles.
Reconstitution
Dissolve with double distilled water.
Warning
For research use only!
Background
Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Tag
Fc
Species
Human
Source
HEK293
BACKGROUND
Background
Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
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