The DNA pull-down assay is an effective method for investigating the interactions between DNA and proteins in vitro. The kit offers scientists a streamlined and effective approach for employing biotinylated DNA as a bait to capture proteins that interact with DNA. This method is suitable for studying interactions between DNA sequences and DNA-binding proteins, including transcription factors, transcription cofactors, and proteins involved in DNA repair mechanisms. This kit is primarily designed for processing animal samples and extracting DNA-binding proteins. The extracted proteins can be directly used for Western Blot or mass spectrometry (MS) identification.
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